PAIN was just one of those games that made you go, "Okay, this is nuts." There are so many ways to toss your hapless victim across the city and for whatever reason, it's oodles of fun. As a result, getting all the Trophies doesn't feel anything like a chore.
Trophies
| 1.5 Mil Pain | Get a Pain Score of at least 1,500,000 |
| 2 Mil Points | Score over 2,000,000 |
| 20X Combo | Get a combo bar of 20 |
| 3 Mil Points | Score over 3,000,000 |
| 500k Pain | Get a Pain Score of at least 500,000 |
| 500k Points | Score over 500,000 |
| Blockbuster (Bronze Trophy) | Use a tank to blow up the Castle Tower |
| Blue Hair | Grab the old lady |
| Bowling Ball! | Grab the Bowling Ball |
| Buzzmonkey (Silver Trophy) | Score 60 Monkeys in Spank the Monkey PAINful with Buzz |
| Camera Boom (Bronze Trophy) | Hit 50 Cameras with Explosions |
| Cross Town | Travel 2000 feet in one launch |
| Frequent Flyer | Travel over 200 miles |
| Gettin' Hoff (Gold Trophy) | Use Tuxedo Hoff to get 69 million in any PAINdemonium Mode. |
| Glass Lass (Bronze Trophy) | Break 500 panes of glass with any female launchable in Mime Toss |
| Grab Master | Make 1000 Grabs |
| Helmet Pi (Bronze Trophy) | Give the Gladiator a ride in the Sports Car |
| King of the Jungle | Grab a Swinging Girder |
| Moon Landing | Reach an Altitude of 300,000 feet |
| Sick and Twisted | Make 500 Grabs |
| Take A Ride | Grab the Train |